![]() It is not a spontaneous process that just happens when building blocks (nutrients) are available, but rather a highly regulated, plastic process controlled by TOR-dependent signaling pathways. ![]() The discovery of TOR led to a fundamental change in how we think about cell growth. TOR, which was originally discovered in yeast, is conserved in all eukaryotes including plants, worms, flies, and mammals. Target of rapamycin (TOR) is a highly conserved serine/threonine kinase that controls cell growth and metabolism in response to nutrients, growth factors, cellular energy, and stress.
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